日本気管食道科学会会報 第73巻2号
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成したspheroidを用いての立体臓器の作成を予定している。4.結語 本研究は将来的に自己細胞のみでの移植片作成を実現する可能性を有し,臨床応用へとつながることが期待される。 本抄録/会議録に関連し,開示すべき利益相反関係にある企業などはありません。文  献日気食会報,73(2),20221) Haykal S, Salna M, Waddell TK, et al:Advances in tracheal reconstruction. Plast Reconst Sur Glob Open 2(7):e178, 2014.2) Dikina AD, Strobel HA, Lai BP, et al:Engineered cartilaginous tubes for tissue replacement via self-assembly and fusion of human mesenchymal stem cell constructs. Biomaterials 52:452─462, 2015.3) Gonfiotti A, Jaus MO, Barale D, et al:The first tissue-engineered airway transplantation:5-year follow-up results. Lancet 383:238─244, 2014.4) Jungebluth P, Haag JC, Sjöqvist S, et al:Tracheal tissue engineering in rats. Nat Protoc 9:2164─2179, 2014.5) Kelm JM, Lober V, Snederker JG, et al:A novel concept for scaffold-free vessel tissue engineer-ing:self-assembly of microtissue building blocks. J Biotechnol 148:46─55, 2010.6) Nakayama K:In vitro biofabrication of tissues and organs. Biofabrication, Ch. 1, pp. 1─21, William Andrew, Oxford, UK, 2013.7) Machino R, Matsumoto K, Taniguchi D, et al:Re-placement of rat tracheas by layered, trachea-like, scaffold-free structures of human cells using a bio-3D printing system. Adv Healthc Mater 8(7):e1800983, 2019.8) Taniguchi D, Matsumoto K, Tsuchiya T, et al:Scaffold-free trachea regeneration by tissue engi-neering with bio-3D printing. Interact Cardiovasc Thorac Surg 26(5):745─752, 2018.9) Takeoka Y, Matsumoto K, Taniguchi D, et al:Re-generation of esophagus using a scaffold-free bio-mimetic structure created with bio-three-dimen-sional printing. Plos One 14(3):e0211339, 2019.180

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